Moxisylyte

Chemical compound
  • G04BE06 (WHO) C04AX10 (WHO)
Identifiers
  • 4-[2-(Dimethylamino)ethoxy]-5-isopropyl-2-methylphenyl acetate
CAS Number
  • 54-32-0 checkY
PubChem CID
  • 4260
DrugBank
  • DB09205 checkY
ChemSpider
  • 4110
UNII
  • PW8QYA7KI0
KEGG
  • D08239 checkY
CompTox Dashboard (EPA)
  • DTXSID4023339 Edit this at Wikidata
ECHA InfoCard100.000.186 Edit this at WikidataChemical and physical dataFormulaC16H25NO3Molar mass279.380 g·mol−13D model (JSmol)
  • Interactive image
  • CC1=CC(=C(C=C1OC(=O)C)C(C)C)OCCN(C)C
InChI
  • InChI=1S/C16H25NO3/c1-11(2)14-10-15(20-13(4)18)12(3)9-16(14)19-8-7-17(5)6/h9-11H,7-8H2,1-6H3
  • Key:VRYMTAVOXVTQEF-UHFFFAOYSA-N
  (verify)

Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction.[1] It is an α1-adrenergic antagonist.[2] In the United Kingdom, Moxisylte is marketed as Opilon (Archimedes Pharma UK Ltd) and is used for the short-term treatment of primary Raynaud's syndrome. This is a condition where the fingers and toes become discoloured and is triggered by responses to cold, or emotional distress. Opilon tablets help by improving blood circulation to the extremities.[3][4]

References

  1. ^ British National Formulary 69, Chapter2.6.4, page 142
  2. ^ Sakakibara R, Hattori T, Uchiyama T, et al. (March 2000). "Are alpha-blockers involved in lower urinary tract dysfunction in multiple system atrophy? A comparison of prazosin and moxisylyte". J. Auton. Nerv. Syst. 79 (2–3): 191–5. doi:10.1016/S0165-1838(99)00105-8. PMID 10699651.
  3. ^ British National Formulary 70, page 205
  4. ^ "Opilon tablets - Patient Information Leaflet (PIL) - (eMC)". www.medicines.org.uk.


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α1
Agonists
Antagonists
α2
Agonists
Antagonists
β
Agonists
Antagonists
  • See also: Receptor/signaling modulators
  • Dopaminergics
  • Serotonergics
  • Monoamine reuptake inhibitors
  • Monoamine releasing agents
  • Monoamine metabolism modulators
  • Monoamine neurotoxins


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