PGAM5

PGAM5
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3MXO, 3O0T
Identifiers
Aliases	PGAM5, BXLBV68, PGAM family member 5, mitochondrial serine/threonine protein phosphatase
External IDs	OMIM: 614939; MGI: 1919792; HomoloGene: 14597; GeneCards: PGAM5; OMA:PGAM5 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q24.33 Start 132,710,819 bp[1] End 132,722,734 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 F Start 110,406,996 bp[2] End 110,417,779 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle mucosa of transverse colon muscle of thigh right adrenal gland islet of Langerhans right lobe of liver appendix left adrenal gland right adrenal cortex left adrenal cortex Top expressed in superior cervical ganglion endocardial cushion interventricular septum mandibular prominence neural tube medial ganglionic eminence barrel cortex maxillary prominence piriform cortex subiculum More reference expression data BioGPS n/a
Gene ontology Molecular function phosphatase activity phosphoprotein phosphatase activity hydrolase activity GTPase activator activity protein binding protein-containing complex binding protein serine/threonine phosphatase activity Cellular component integral component of membrane membrane mitochondrion mitochondrial outer membrane Biological process protein dephosphorylation necroptosis programmed cell death dephosphorylation positive regulation of GTPase activity macroautophagy negative regulation of cold-induced thermogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 192111 72542 Ensembl ENSG00000247077 ENSMUSG00000029500 UniProt Q96HS1 Q8BX10 RefSeq (mRNA) NM_138575 NM_001170543 NM_001170544 NM_001163538 NM_028273 RefSeq (protein) NP_001164014 NP_001164015 NP_612642 NP_001157010 NP_082549 Location (UCSC) Chr 12: 132.71 – 132.72 Mb Chr 5: 110.41 – 110.42 Mb PubMed search [3] [4]
Wikidata
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PGAM family member 5 (PGAM5), also known as mitochondrial Serine/threonine-protein phosphatase PGAM5 is related to phosphoglycerate mutase family. It, in humans, is encoded by the PGAM5 gene on chromosome 12.^[5][6]

References

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Serine/threonine-protein phosphatase PGAM5, mitochondrial